3D Bioprinting Technology in Tissue Engineering Printing Method and Material Selection

This project offers a detailed evaluation framework for 3D bioprinting used in tissue engineering, emphasizing how printing methods and material choices affect each other. We systematically examine extrusion, inkjet, and light‑based bioprinting, looking at factors such as shear stress, resolution, and printing speed. At the same time, we evaluate how to choose bioinks—natural hydrogels, synthetic polymers, or composites—based on their flow behavior, crosslinking mechanisms, and biocompatibility. A multi‑criteria decision model helps match a specific tissue target with the best printing method and material mix. We use computational fluid dynamics (CFD) simulations to model bioink flow through tiny nozzles, predicting cell damage from shear and how well the printed structure retains

its shape. The framework acts as a guide to optimize scaffold fabrication, keeping the structure strong and cells alive for regenerative‑medicine applications. In short, this work provides a systematic way to balance printability and biological function in scaffold design.

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