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Mechanical Characterization of 3D-Printed Patterned Membranes for Cardiac Tissue Engineering: An Experimental and Numerical Study

Mechanical Characterization 3D-Printed Patterned Membranes is a M.Tech project topic for Mechanical Engineering. Explore the IEEE-style abstract,…

Mechanical Characterization 3D-Printed Patterned Membranes is a M.Tech project topic for Mechanical Engineering. It gives students a clear starting point for research, implementation planning, and documentation.

Mechanical Characterization 3D-Printed Patterned Membranes Project Details

Abstract

Myocardial infarctions often cause permanent damage to the tissues of the heart, which means that high-level therapeutic options are required. Cardiac patches and devices that use epicardial restraint may treat these diseases and prevent serious complications. A major difficulty in the creation of these cardiac patches is the reconstruction of the myocardium's complex fibrillar architecture and its anisotropic, localized elastic properties. This study attempts to address this issue by creating a new type of biomaterial ink made from chitosan, gelatin, and guar gum. The ink was then used to create structures via a custom 3D printer that produced patterned anisotropic membranes, which are intended to mimic the structure of cardiac

tissue. The printed membranes were studied to characterize their mechanical properties. The data from these experiments was critical in constructing a more advanced numerical model that can predict the elastic response of different geometries of membranes with the possibility of adjustable elasticity. The goal is to align the mechanical response of designed constructs with that of the myocardial component of natural heart tissue in order to further develop the cardiac tissue engineering field.

Reference Paper Mechanical Characterization of 3D-Printed Patterned Membranes for Cardiac Tissue Engineering: An Experimental and Numerical Study
Domain Mechanical Engineering
Sub-Domain Design & Manufacturing / Additive Manufacturing / Bioprinting
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